Apoptosis
This odd word designates the process by which cells can die without causing harm to the adjacent tissues. That’s why it’s a complicated and regulated physiological mechanism. Indeed, it’s tough to tell how many cells our bodies produce each day, but one thing is sure : it’s a big number. So cells do have to die in order to regenerate tissues.
Apoptosis will involve a cascade of protein activations which implies the cleavage of these proteins. Cleaved proteins can be tagged and observed using a fluorescence microscope. Above, cells on the left are left untreated, cells on the right were treated with Staurosporine. With green and red dyes we can see proteins, alpha-tubulin and phospho-H3 histone, involved in proliferating cells. On the right, the blue dye shows cleaved PARP, a major marker of apoptosis. In short, these cells are dying.

Apoptosis

This odd word designates the process by which cells can die without causing harm to the adjacent tissues. That’s why it’s a complicated and regulated physiological mechanism. Indeed, it’s tough to tell how many cells our bodies produce each day, but one thing is sure : it’s a big number. So cells do have to die in order to regenerate tissues.

Apoptosis will involve a cascade of protein activations which implies the cleavage of these proteins. Cleaved proteins can be tagged and observed using a fluorescence microscope. Above, cells on the left are left untreated, cells on the right were treated with Staurosporine. With green and red dyes we can see proteins, alpha-tubulin and phospho-H3 histone, involved in proliferating cells. On the right, the blue dye shows cleaved PARP, a major marker of apoptosis. In short, these cells are dying.

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